Paulo Dybala struck twice in a stunning first half and Giorgio Chiellini added a rare third after the break as the hosts claimed a commanding advantage ahead of next week’s second leg.

Barcelona’s only hope is to repeat their feat of the previous round, when they recovered from a 4-0 first-leg loss to Paris Saint-Germain by beating the French side 6-1 at home.

But on this evidence a second comeback looks unlikely after Juventus dominated proceedings with the help of Dybala’s brilliant first-half brace.

Luis Enrique’s men, smarting from a domestic defeat to Malaga at the weekend, fell behind with seven minutes on the clock.

The superb Juan Cuadrado found Dybala on the right side of the box and the striker curled home an excellent left-foot shot.

Barcelona could have grabbed an equaliser after 20 minutes when Lionel Messi threaded the ball to Andres Iniesta but the midfielder’s low shot was tipped wide by Gianluigi Buffon.

Moments later, Juventus surged down the left flank and Mario Mandzukic crossed for the unmarked Dybala, who fired his second of the game past ter Stegen to put the Italians 2-0 up.

Messi had an effort ruled out for offside on the half-hour before Juventus came close to increasing their lead when Cuadrado pulled back for Miralem Pjanic who blazed over the bar.

Barcelona started the second half in much better fashion with Messi rolling an effort inches wide of the upright and Buffon just beating Luis Suarez to an Ivan Rakitic through-ball.

But Juventus, marshalled by a towering performance by Brazilian Alex Santos, held out and Messi’s last chance to reduce the deficit came to an end when he spun a free-kick into the Italians’ wall.

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