LONDON: Arsenal lost their grip on the FA Cup as a Gabriel Magalhaes own goal gave Southampton a deserved win in their fourth-round tie on the south coast.

Mikel Arteta made seven changes to his side and was without captain Pierre-Emerick Aubameyang for personal reasons as the Gunners were outplayed, losing their grip on the trophy following a 1-0 defeat at St Mary’s.

Southampton should have won by a bigger margin but now face a trip to Wolves in round five as Gabriel’s poor return to the Arsenal side was capped by accidentally deciding the tie in favour of the hosts.

Cheltenham Town narrowly missed out on perhaps the biggest FA Cup upset ever, as Manchester City scored three times in the final 10 minutes to come from behind and win 3-1.

The League Two side went ahead just before the hour through Alfie May’s close-range finish after a Ben Tozer long throw caused mayhem in the City box.

Just as the Robins could start dreaming of completing one of the most seismic shocks in the competition’s 150-year history, a string of substitutions changed the game in the Premier League giants’ favour.

Phil Foden fired in an 81st-minute equaliser and Gabriel Jesus quickly followed that up to put City ahead.

Ferran Torres’ injury-time goal meant the scoreline ultimately did not reflect just how close Pep Guardiola’s team came to a hugely embarrassing result.

West Ham cruised into the FA Cup fifth round with a routine 4-0 home win over Sky Bet League One side Doncaster.

David Moyes made eight changes from the victory against West Brom, but first-half goals from Pablo Fornals and Andriy Yarmolenko put his side firmly in control.

After Andy Butler put through his own net, debutant Oladapo Afolayan added the cherry on top with a late fourth.

It sets up a last-16 meeting with one of Manchester United or Liverpool for the Hammers, who have now won their last five matches.

Yves Bissouma’s stunning strike helped Brighton avoid an FA Cup upset as they scraped into the fifth round with a 2-1 win over League One Blackpool.

Albion midfielder Bissouma, who has been linked with a host of Europe’s top clubs in recent weeks, underlined his undoubted ability by opening the scoring with a thunderous drive from fully 30 yards.

The visitors briefly levelled through Gary Madine’s close-range finish but were unable to claim a second successive Premier League scalp as Seagulls midfielder Steven Alzate claimed a fortuitous second-half winner.

Albion’s narrow victory books a fifth-round trip to either Brentford or Leicester and provides a timely confidence boost ahead of Wednesday’s top-flight showdown with fellow strugglers Fulham.

Sheffield United secured just their third win of the season as fans’ favourite Billy Sharp helped Chris Wilder’s men avoid an FA Cup upset against Plymouth.

The Blades have endured a wretched campaign but the Premier League’s bottom side have shown flickers of life recently, making it three wins from four matches in all competitions on Saturday.

Veteran striker Sharp was the key man at Bramall Lane, providing a lovely cross for Chris Basham’s opener before scoring a fine goal early in the second half of a 2-1 fourth-round win against League One side Plymouth.

Panutche Camara’s goal made it a nervy final 15 minutes, but the Blades held on to set up a home fifth-round tie against Bristol City.