LONDON: Both Manchester clubs must overturn first-leg deficits to reach the quarter-final of the Europa League.

Manchester United suffered their second successive home defeat in the competition as a swashbuckling Athletic Bilbao came from behind to secure a deserved 3-2 victory in their last-16 first-leg tie at Old Trafford.

Wayne Rooney started and ended the scoring to give the Red Devils some hope in the return leg next week.

But they will have to go some to overcome an impressive Bilbao outfit who levelled through Fernando Llorente before Oscar de Marcos added a superb second and Iker Muniain made it 3-1 late on, before Rooney’s injury-time penalty made it 3-2.

Brazilian defender Xandao condemned a below-par Manchester City to a 1-0 defeat in the first leg of their Europa League tie against Sporting.

Xandao beat Joe Hart with a clever close-range backheel after 51 minutes as the Portuguese side controlled most of the last-16 encounter at the Jose Alvalade Stadium. Hart also made two good saves but City did have chances with Gareth Barry and Aleksandar Kolarov going close, Mario Balotelli heading against the bar and Sergio Aguero almost breaking through late on.

Atletico Madrid raced into a 3-0 lead inside 37 minutes of their Europa League last 16 first leg at home to Besiktas, but had to settle for a 3-1 win.Eduardo Salvio scored twice in four minutes to put the hosts in control and they were cruising when Adrian Lopez added a third.

But Simao, playing against his former club, pulled a goal back for the Turks eight minutes into the second half to give them hope for the second leg.

PSV Eindhoven scored twice late on to keep their hopes in the competition alive, despite being totally outplayed by Valencia in their 4-2 defeat at the Mestalla.

Roberto Soldado scored twice, the second a penalty, after Victor Ruiz’s opener as the hosts stunned PSV with three first-half goals.

The Dutch side looked down and out when Pablo Piatti added a fourth – the 10th goal PSV have conceded in five days following their 6-2 Eredivisie defeat by FC Twente on Sunday – but an Ola Toivonen penalty in the 83rd minute and another goal from Georgino Wijnaldum in the 90th minute got them back in the tie.

Luuk de Jong scored a hugely fortunate penalty to give FC Twente a 1-0 home leg win over Schalke. The striker clipped his own heels just outside the area and went down, with defender Joel Matip in close attendance. But Scottish referee Craig Thompson pointed to the spot and sent off Matip before De Jong smashed the 61st-minute penalty into the roof of the net.

AZ Alkmaar took a 2-0 first leg lead over Udinese thanks to goals from Maarten Martens (63) and Erik Falkenburg (84).

Hannover drew 2-2 at Standard Liege, Mame Diouf scoring the equaliser in the 56th minute.

Lars Stindl’s penalty put the Germans in front in the 22nd minute, but goals from Yoni Buyens and Mohamed Tchite turned the game around before the break.

Olympiacos won 1-0 in Ukraine against Metalist Kharkiv.

David Fuster scored the only goal of the game five minutes after the break, and the hosts had Edmar sent off eight minutes from time.